Myeloma Drug Glossary Dictionary

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This is one of those things that I’m going to put into a nice graphic when I have the time. For now, hopefully this table proves useful as a thesaurus of myeloma drugs, and their brand names vs generic drug names.

Myelo – A prefix meaning marrow or of the spine

Myeloma – a tumor of plasma cells, usually in the bone marrow or spine

Multiple Myeloma – same as myeloma – since myeloma technically means ONE tumor of plasma cells, multiple myeloma relays that there are usually more than one tumor of plasma cells

dexamethasone – steroid commonly used in treatment of myeloma. Used both to interfere with fast growing cells (cancer cells) and to reduce or block allergic reactions to other treatments – this is why you can’t sleep

Selinexor – treatment drug that blocks cellular export of proteins involved in cancer-cell growth (newish – approved 2019) – Approved to be used with bortezomib and dexamethasone (in place of Revlimid)

Revlimid – brand name for lenalidomide – part of the RVd (Revlimid, Velcade, dexamthasone standard induction treatment cocktail) – This is why you have fatigue.

Velcade – brand name for bortezomib – the V in RVd – this is why your hands and/or feet hurt (neuropathy) also fatigue

induction or induction therapy – the first in a series of treatments, like being inducted into the club, only the club sucks, it’s a cancer club. For multiple myeloma patients, induction is usually taking chemotherapy pills for a while with the goal of reducing (eliminating) the amount of cancer in the body and reduce (eliminate) tumors caused by multiple myeloma. Induction therapy comes before stem cell transplant (ASCT) if your treatment includes a transplant.

ASCT – autologous stem cell transplant – a stem cell transplant that uses your own stem cells (as opposed to getting stem cells from a donor) – usually a treatment for those under 70 and in good health

melphalan – the drug they give you at the beginning of ASCT that destroys your immune system – may be used as an ongoing treatment at a much lower dosage

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